sphingomyelin phosphodiesterase
Pronunciation: sfing′gō-mī′ĕ-lin fos′fō-dī-es′tĕr-ās
Definition: An enzyme catalyzing hydrolysis of sphingomyelin to N-acylsphingosine (a ceramide) and phosphocholine; a deficiency of this enzyme is associated with type I Niemann-Pick disease.
Synonym(s): sphingomyelinase
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