scleroderma
Pronunciation: sklē′rō-der′mă
Definition: Thickening and induration of the skin caused by new collagen formation, with atrophy of pilosebaceous follicles; either a manifestation of progressive systemic sclerosis or localized (morphea).
See: systemic sclerosis, morphea
Synonym(s): systemic scleroderma, systemic sclerosis2
[sclero- + G. derma, skin]
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Examples: glitazone, GI cocktail, etc.

