scleredema
Pronunciation: sklēr-e-dē′mă
Definition: Hard nonpitting edema of the skin of the dorsal aspect of the upper body and extremities, giving a waxy appearance and no sharp demarcation; seen in diabetic patients and in scleredema adultorum.
[scler- + G. oidēma, a swelling (edema)]
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Examples: glitazone, GI cocktail, etc.

