Pronunciation: shis′, skis′tō-sō-mī′ă-sis
Definition: Infection with a species of Schistosoma; manifestations of this often chronic and debilitating disease vary with the infecting species but depend in large measure on tissue reaction (granulation and fibrosis) to the eggs deposited in venules and in the hepatic portals, the latter resulting in portal hypertension and esophageal varices, as well as liver damage leading to cirrhosis.
See: tropic diseases, under disease
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Examples: glitazone, GI cocktail, etc.