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Definition: a rare disorder resulting from renal tubular damage of a variety of etiologies; mimics adrenocortical insufficiency in that abnormal renal loss of sodium chloride occurs, accompanied by hyponatremia, azotemia, acidosis, dehydration, and vascular collapse.
Synonym(s): salt-losing syndrome, Thorn syndrome
Examples: glitazone, GI cocktail, etc.
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