Reed-Sternberg cell
Pronunciation: rēd shtĕrn′bĕrg
Definition: large transformed lymphocytes, probably B cell in origin, generally regarded as pathognomonic of Hodgkin disease; a typical cell has a pale-staining acidophilic cytoplasm and one or two large nuclei showing marginal clumping of chromatin and unusually conspicuous deeply acidophilic nucleoli; binucleate Reed-Sternberg cell frequently shows a mirror-image form (mirror-image cell).
Synonym(s): Reed cell, Sternberg cell, Sternberg-Reed cell
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Examples: glitazone, GI cocktail, etc.

