Pronunciation: pō′lē - ō - en - sef′ă - lō - mă - lā′shē - ă
Definition: Cerebrocortical necrosis in sheep and goats, also seen in cattle, deer, and antelope. Associated with thiamine deficiency, water deprivation-sodium ion toxicosis, lead poisoning, and particularly with high dietary sulfur levels leading to high hydrogen sulfide and acetic acid levels in the rumen, which adversely affect carbohydrate metabolism.
Synonym(s): cerebrocortical necrosis
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Examples: glitazone, GI cocktail, etc.