Peutz-Jeghers syndrome
Pronunciation: pŭtz jā′gĕrz
Definition: generalized hamartomatous multiple polyposis of the intestinal tract, consistently involving the jejunum, associated with melanin spots of the lips, buccal mucosa, and fingers; autosomal dominant inheritance, caused by mutation in the serine/threonine kinase gene (STK11) on chromosome 19p.
Synonym(s): Jeghers-Peutz syndrome, Peutz syndrome
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Examples: glitazone, GI cocktail, etc.
