Medical Term:

Peutz-Jeghers syndrome

Pronunciation: pŭtz jā′gĕrz

Definition: generalized hamartomatous multiple polyposis of the intestinal tract, consistently involving the jejunum, associated with melanin spots of the lips, buccal mucosa, and fingers; autosomal dominant inheritance, caused by mutation in the serine/threonine kinase gene (STK11) on chromosome 19p.

Synonym(s): Jeghers-Peutz syndrome, Peutz syndrome

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