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Definition: a congenital syndrome with hydrophthalmia, cataracts, mental retardation, aminoaciduria, reduced ammonia production by the kidney, and vitamin D–resistant rickets; X-linked recessive inheritance, caused by mutation in the oculocerebrorenal gene (OCRL) on Xq.
Synonym(s): Lowe syndrome, Lowe-Terrey-MacLachlan syndrome
Examples: glitazone, GI cocktail, etc.
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