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Definition: an autosomal recessively inherited metabolic defect in the absorption of methionine that is converted by intestinal bacteria to α-hydroxybutyric acid; characterized by diarrhea, tachypnea, and marked urinary excretion of α-hydroxybutyric acid (causing an odor like that of an oasthouse).
[oast, kiln for drying hops, malt, or tobacco]
Examples: glitazone, GI cocktail, etc.
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