Medical Term:

N5, N10-methylenetetrahydrofolate reductase

Pronunciation: meth′il-ēn-tet′ră-hī′drō-fō′lāt rĕ-duk′tās

Definition: An enzyme that converts N5,N10-methylenetetrahydrofolate to N5,N10-methenyltetrahydrofolate using NADP+; a deficiency of this enzyme results in an accumulation of l-homocysteine and severe neurological disturbances.

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