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Definition: an inflammatory myopathy detected in patients with diffuse arthromyalgias and severe fatigue; characterized by muscle infiltration by granular periodic acid-Schiff reagent–positive macrophages and lymphocytes. The inclusions detected in the macrophages have been identified as aluminum hydroxide, an immunostimulatory compound used as a vaccine adjuvant.
Examples: glitazone, GI cocktail, etc.
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