lichen sclerosus et atrophicus
Definition: an eruption consisting of pruritic white atrophic papules and plaques that may be discrete or confluent and may contain a central depression or a black keratotic plug microscopically showing epidermal hyperkeratosis and atrophy, superficial dermal edema and homogenization, and mid-dermal inflammation; occurs most commonly in prepubertal and postmenopausal females; vulval involvement was formerly called kraurosis vulvae.
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Examples: glitazone, GI cocktail, etc.
