Medical Term:

leptin

Pronunciation: lep′tin

Definition: A helical protein secreted by adipose tissue and acting on a receptor site in the ventromedial nucleus of the hypothalamus to curb appetite and increase energy expenditure as body fat stores increase. Leptin levels are 40% higher in women, and show a further 50% rise just before menarche, later returning to baseline levels. Levels are lowered by fasting and increased by inflammation.

Synonym(s): OB protein

[G. leptos, thin, + -in]

Hide
(web4)