ketole group
Pronunciation: kē′tōl grūp
Definition: Carbons 1 and 2 of a 2-ketose (HOCH2CO—); trans-ketolation from d-xylose 5-phosphate to C-1 of aldoses is important in various metabolic pathways involving carbohydrates (photosynthesis, Dickens shunt); the two-carbon unit is transferred as α,β-dihydroxyethylthiamin pyrophosphate.
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Examples: glitazone, GI cocktail, etc.
