Definition: abnormal hemoglobins showing left-shifted oxygen dissociation curves and associated familial erythrocytosis. Forty-three high-affinity hemoglobins have been described, including, Hb Chesapeake, Hb J Capetown, Hb Malmo, Hb Yakima, Hb Kemp, Hb Ypsi (Ypsilanti), Hb Hiroshima, Hb Rainier, and Hb Bethesda.
Synonym(s): high-oxygen-affinity hemoglobin
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