Medical Term:

heparan N-sulfatase

Pronunciation: hep′ă-ran sŭl′fă-tās

Definition: An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N-sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated with mucopolysaccharidose IIIA (Sanfilippo syndrome A).

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