Medical Term:

fructose-bisphosphate aldolase

Pronunciation: fruk′tōs bis-fos′fāt al′dol-ās

Definition: an enzyme reversibly cleaving fructose 1,6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate; also acts on certain ketose 1-phosphates; deficient in individuals with hereditary fructose intolerance (aldolase B isozyme); a deficiency of aldolase A leads to erythrocyte aldolase deficiency with nonspherocytic hemolytic anemia.

Synonym(s): 1,6-diphosphofructose aldolase, 1-phosphofructaldolase, diphosphofructose aldolase, fructoaldolase, fructose 1,6-bisphosphate triosephosphate-lyase, fructose 1,6-diphosphate aldolase, fructose 1-monophosphate aldolase, fructose 1-phosphate aldolase, fructose-diphosphate aldolase, ketose-1-phosphate aldolase, phosphofructoaldolase, SMALDO, zymohexase

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