Definition: High molecular weight multifunctional glycoproteins found on cell surface membranes and in blood plasma and other body fluids. Fibronectins are thought to function as adhesive ligandlike molecules that play a role in contact inhibition; also known as large external transformation sensitive protein (LETS), which is reduced after cells become transformed.
[L. fibra, fiber, + nexus, interconnection]
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Examples: glitazone, GI cocktail, etc.