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Definition: progressive atrophy of the iris without inflammatory signs, characterized by patchy loss of all layers of the iris with hole formation, migration of the pupil, degeneration of the corneal endothelium, peripheral anterior synechiae, and secondary glaucoma; usually unilateral, predominantly affecting women in their middle years.
See Also: iridocorneal syndrome
Examples: glitazone, GI cocktail, etc.
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