Definition: a febrile condition caused by cutaneous dissemination of herpesvirus type 1, occurring most commonly in children, consisting of a widespread eruption of vesicles that rapidly become umbilicated pustules; clinically indistinguishable from a generalized vaccinia. The two may be distinguished by electron microscopy or demonstration of inclusion bodies in smears, which are intranuclear in eczema herpeticum and intracytoplasmic in eczema vaccinatum.
Synonym(s): pustulosis vacciniformis acuta
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