Medical Term:

dihydropyrimidine dehydrogenase

Pronunciation: dī-hī′drō-pī-rim′ĭ-dēn dē-hī′drō-jen-ās′

Definition: An enzyme in pyrimidine biosynthesis that reacts 5,6-dihydrouracil with NADP+ to form uracil and NADPH; it also acts on dihydrothymine; a deficiency of this enzyme can result in hyperuracil thyminuria.

Synonym(s): dihydrouracil dehydrogenase

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