deoxyribonuclease I
Definition: an endonuclease that cleaves primarily double-stranded DNA to a mixture of oligodeoxyribonucleotides, each ending in a 5′-phosphate; streptodornase is a similar enzyme. Under appropriate conditions, it can produce single-strand nicks in DNA; used in nick translation and in the mapping of hypersensitive sites.
Synonym(s): pancreatic deoxyribonuclease, thymonuclease
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.
