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Definition: loss of elastic and muscle fibers in the aortic media, with accumulation of mucopolysaccharide, sometimes in cystlike spaces between the fibers; a disease of unknown cause, which may be inherited and predisposes to dissecting aneurysms.
Synonym(s): Erdheim disease, medionecrosis aortae idiopathica cystica, medionecrosis of the aorta, mucoid medial degeneration
Examples: glitazone, GI cocktail, etc.
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