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Pronunciation: sī′klō-fil′inz
Definition: Intracellular proteins associated with heat shock proteins and other molecules (e.g., glucocorticoid receptors). Cyclophilins mediate immunosuppressive actions of antirejection drugs (e.g., cyclosporine and FK-506).
[cyclo- + G. philia, love, attraction, + -in]
Examples: glitazone, GI cocktail, etc.
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