coregulators
Pronunciation: kō′reg′yū-lā-tŏrz
Definition: Nuclear proteins that participate in the regulation of transcription of genes that are responsive to ligand-dependent transcription factors. Distinguished loosely into coactivators or corepressors depending on the direction of coregulation. Defective coregulators have been associated with human disease.
[co- + regulator]
See Also: coactivator, corepressors
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