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Pronunciation: sik-lō-fil′inz
Definition: Intracellular proteins associated with heat shock proteins and other molecules (glucocorticoid receptor). Ciclophilins mediate immunosuppressive actions of antirejection drugs (ciclosporin and FK-506).
[ciclosporin + G. philia, affinity, attaction, + -in]
Examples: glitazone, GI cocktail, etc.
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