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Definition: production of a yellow-brown to brown coloration in normal and abnormal cells containing epinephrine and norepinephrine when fresh tissue slices are placed in a dichromate-chromate mixture overnight; useful for detection of pheochromocytoma (adrenal medulla) and other tumors that produce catecholamines.
See Also: chromaffin
Examples: glitazone, GI cocktail, etc.
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