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Definition: hydatidiform mole in which there is an unusual degree of invasion of the myometrium or its blood vessels, causing hemorrhage, necrosis, and occasionally rupture of the uterus or embolism of molar tissue to the lungs; there is marked proliferation of the trophoblast, but avascular villi may also be found.
Synonym(s): invasive mole
Examples: glitazone, GI cocktail, etc.
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