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Definition: a slowly progressive familial chorea with associated mental deterioration, diminished deep tendon reflexes, bilateral atrophy of the putamen and caudate nuclei and acanthocytosis (thorny appearance of blood erythrocytes); the disorder typically begins around late adolescence; inheritance is usually autosomal recessive.
Synonym(s): acanthocytosis with chorea
Examples: glitazone, GI cocktail, etc.
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