cholinesterase reactivator
Pronunciation: kō′lin-es′ter-ās rē-ak′ti-vā′tōr
Definition: A drug that reacts directly with the alkylphosphorylated enzyme to free the active unit; the drugs used therapeutically to reactivate phosphorylated forms of acetylcholinesterase are oximes, diacetylmonoxime, monoisonitrosoacetone, 2-pralidoxime.
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Examples: glitazone, GI cocktail, etc.
