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Definition: a chromosomal disorder characterized by iris colobomas (resembling the vertical pupils of a cat), downslanting palpebral fissures, anal atresia, preauricular tags and/or pits, heart and renal malformations, and, occasionally, mild mental retardation; associated with chromosome partial tetrasomy 22.
Synonym(s): Schmid-Fraccaro syndrome
Examples: glitazone, GI cocktail, etc.
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