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Stedman's Medical Dictionary
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Stedman's > C1 esterase inhibitor

C1 esterase inhibitor

an α2-neuraminoglycoprotein that inhibits the enzymatic activity of C1 esterase, the activated first component of complement. A deficiency of this inhibitor results in a lack of inhibition of C1r and C1s leading to uncontrolled activation of the complement cascade and angioedema.