butyrate:CoA ligase
Pronunciation: byū′ti-rāt lī′gās
Definition: Fatty acid thiokinase (medium chain), a ligase forming acyl-CoA's from medium-chain fatty acids and CoA with the conversion of ATP to AMP and pyrophosphate. A key step in the activation of fatty acids.
Synonym(s): acyl-activating enzyme2, butyryl-CoA synthetase, octanoyl-CoA synthetase
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Examples: glitazone, GI cocktail, etc.
