Definition: an apolipoprotein found in several plasma lipoprotein particles including chylomicrons, VLDL, and HDL. Three major isoforms are encoded by three common alleles at the Apo E locus: E2, E2, and E4. The E2 allele is associated with lower total plasma cholesterol and LDL cholesterol than is E3, whereas E4 is associated with higher LDL and total cholesterol than E3.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.