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Definition: a lesion with extensive and rapid death of parenchymal cells of the liver, sometimes with fatty degeneration of the size of the organ; the necrosis may result from fulminant viral infection or chemical poisoning; associated with jaundice.
Synonym(s): acute parenchymatous hepatitis, acute yellow atrophy of the liver, Rokitansky disease1
Examples: glitazone, GI cocktail, etc.
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