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Definition: complex of N-carboxybiotin (biotin + CO2) and an enzyme; the form in which carbon dioxide is added to other molecules in carboxylations, to methylcrotonyl-CoA to form β-methylglutaconyl in the catabolism of leucine, and to acetyl-CoA to form malonyl-CoA.
See Also: acetyl-CoA carboxylase
Examples: glitazone, GI cocktail, etc.
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