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Pronunciation: ak′rō-sklĕ-rō′sis
Definition: Stiffness and tightness of the skin of the fingers, with atrophy of the soft tissue and osteoporosis of the distal phalanges of the hands and feet; a limited form of progressive systemic sclerosis occurring with Raynaud phenomenon and scleroderma of the forearms.
See: CREST syndrome
Synonym(s): acroscleroderma, sclerodactyly, sclerodactylia
Examples: glitazone, GI cocktail, etc.
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