Definition: an eruption, predominantly of the face, upper back, and chest, composed of comedones, cysts, papules, and pustules on an inflammatory base; the condition occurs in a majority of people during puberty and adolescence, due to androgenic stimulation of sebum secretion, with plugging of follicles by keratinization, associated with proliferation of Propionibacterium acnes. Follicular suppuration may lead to scarring. Topical treatments include tretinoin, benzoyl peroxide, and antibiotics. Sunlight, systemic antibiotics, and oral 13-cis-retinoic acid (except in pregnancy) are also effective.
See Also: acne
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Examples: glitazone, GI cocktail, etc.