Medical Term:
3-oxoacid-CoA transferase
Pronunciation: ok′sō-as′id trans′fĕr-ās
Definition: An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues.
Synonym(s): 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase
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Examples: glitazone, GI cocktail, etc.
