Medication Guide App

ropivacaine (Injection route)

roe-PIV-a-kane

Commonly used brand name(s)

In the U.S.

  • Naropin

Available Dosage Forms:

  • Solution

Therapeutic Class: Anesthetic, Local

Chemical Class: Amino Amide

Uses For ropivacaine

Ropivacaine is a local anesthetic given by injection to cause loss of feeling before and during surgery or labor and delivery. It does not cause loss of consciousness.

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Ropivacaine is given only by or under the immediate supervision of a medical doctor, or by a specially trained nurse, in the doctor's office or in a hospital.

Before Using ropivacaine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ropivacaine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ropivacaine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on ropivacaine have been done only in adolescents and adults, and there is no specific information comparing use of ropivacaine in children with use in other age groups.

Geriatric

Many medicines have not been specifically studied in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ropivacaine in the elderly with use in other age groups. Based on information about similar medicines, it is expected that elderly people will be more sensitive than younger adults to the effects of ropivacaine. This may increase the chance of side effects.

Pregnancy

Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking ropivacaine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ropivacaine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Hyaluronidase
  • Pixantrone
  • St John's Wort

Using ropivacaine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Ciprofloxacin
  • Fluvoxamine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ropivacaine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use ropivacaine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Tobacco

Other Medical Problems

The presence of other medical problems may affect the use of ropivacaine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease—ropivacaine may make your condition worse
  • Kidney disease or
  • Liver disease—Side effects may be more likely in patients with kidney disease or liver disease

Proper Use of ropivacaine

Dosing

The dose of ropivacaine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of ropivacaine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • Your age;
  • Your general physical condition;
  • The reason the medicine is being given; and
  • Other medicines you are taking or will receive before or after ropivacaine is given.

Precautions While Using ropivacaine

For patients going home before the numbness or loss of feeling caused by ropivacaine wears off:

  • During the time that the injected area feels numb, serious injury can occur without your knowing it. Be especially careful to avoid injury until the medicine wears off or feeling returns to the area.

ropivacaine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare
  • Burning or prickling sensation
  • fever
  • itching

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare
  • Back pain
  • difficulty urinating
  • headache
  • pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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