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Generic Name: olopatadine (Ophthalmic route)


Commonly used brand name(s)

In the U.S.

  • Pataday
  • Patanol
  • Pazeo

Available Dosage Forms:

  • Solution

Therapeutic Class: Ophthalmologic Agent

Pharmacologic Class: Antihistamine

Uses For Patanol

Olopatadine ophthalmic (eye) drops is used to treat itching of the eye caused by a condition known as allergic conjunctivitis (pink eye). It works by preventing the effects of certain inflammatory substances, which are produced by cells in your eyes and sometimes cause allergic reactions.

Slideshow: OTC Medication Use In Pregnancy: Wise or Worrisome?

This medicine is available only with your doctor's prescription.

Before Using Patanol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of olopatadine eye drops in children. However, safety and efficacy of olopatadine ophthalmic solution and Patanol® have not been established in children younger than 3 years of age, and of Pataday™ and Pazeo™ have not been established in children younger than 2 years of age.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of olopatadine eye drops in the elderly.


Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Bupropion
  • Donepezil

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of olopatadine

This section provides information on the proper use of a number of products that contain olopatadine. It may not be specific to Patanol. Please read with care.

Your eye doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.

If you are wearing contact lenses, remove them before putting the drops in your eyes. Wait at least 5 or 10 minutes after using this medicine before putting them back in. Do not wear contact lenses if your eyes are red.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

To use the eye drops:

  • First, wash your hands. Tilt your head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eye. Do not blink. Keep the eye closed for 1 or 2 minutes to allow the medicine to cover the eye.
  • If you think you did not get the drop of medicine into your eye properly, repeat the directions with another drop.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For ophthalmic dosage form (eye drops):
    • For treatment of itching of the eye caused by allergic conjunctivitis:
      • Patanol®:
        • Adults and children 3 years of age and older—Put one drop (0.1% solution) in each affected eye two times a day, at least 6 to 8 hours apart.
        • Children younger than 3 years of age—Use and dose must be determined by your doctor.
      • Pataday™ and Pazeo™:
        • Adults and children 2 years of age and older—Put one drop in each affected eye once a day.
        • Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Patanol

Your eye doctor will want to examine your or your child's eye(s) at regular visits to make sure the medicine is working properly and is not causing unwanted effects.

If your or your child's symptoms do not improve or if your condition becomes worse, check with your doctor.

This medicine should not be used for irritation caused by contact lenses.

Patanol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Blurred vision
  • eye irritation or pain
  • swelling of the eyelid

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Headache
  • runny or stuffy nose
  • sore throat
Less common
  • Back pain
  • body aches or pain
  • burning, dryness, itching, or stinging of the eye
  • change in taste
  • chills
  • cough
  • diarrhea
  • feeling of something in the eye
  • general feeling of discomfort or illness
  • increased cough
  • lack or loss of strength
  • loss of appetite
  • muscle aches and pains
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • redness of the eye or inside of the eyelid
  • sensitivity of the eyes to light
  • shivering
  • sneezing
  • sweating
  • tender, swollen glands in the neck
  • trouble sleeping
  • trouble swallowing
  • unusual tiredness or weakness
  • voice changes
  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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