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iobenguane i 131 (Intravenous route)

eye-oh-BEN-gwane I 131

Available Dosage Forms:

  • Solution

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

Uses For iobenguane i 131

Radioiodinated iobenguane is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs.

Radioiodinated iobenguane is used to treat certain kinds of cancer of the adrenal glands.

When very small doses of radioiodinated iobenguane are given, the radioactivity taken up by the adrenal gland helps find tumors of the adrenal glands. An image of the gland on film or on a computer screen can be provided to help with the diagnosis.

The information that follows applies only to the use of radioiodinated iobenguane in treating cancer of the adrenal gland.

Radioiodinated iobenguane is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.

Before Using iobenguane i 131

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For iobenguane i 131, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to iobenguane i 131 or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children and adolescents are especially sensitive to the effects of radiation. This may increase the chance of side effects during and after treatment. Be sure you have discussed this with your doctor.

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Geriatric

Radioiodinated iobenguane has been used in older people and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking iobenguane i 131, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using iobenguane i 131 with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Labetalol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of radioiodinated iobenguane. Make sure you tell your doctor if you have any other medical problems.

Proper Use of iobenguane i 131

Dosing

The dose of iobenguane i 131 will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of iobenguane i 131. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

iobenguane i 131 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare
  • Pale skin
  • sore throat and fever
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare
  • Flushing of skin
  • nausea
  • slight and temporary increase in blood pressure

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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