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Medications for Peripheral Neuropathy

Other names: Neuropathy

Peripheral neuropathy is failure of the nerves that carry information to and from the brain and spinal cord. This produces symptoms like pain, loss of sensation, and inability to control muscles.

Drugs used to treat Peripheral Neuropathy

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Qutenza Off-label 4.0 5 reviews for Qutenza to treat Peripheral Neuropathy
Rx B N
Generic name:
capsaicin topical
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
pregabalin Off-label 6.6 43 reviews for pregabalin to treat Peripheral Neuropathy
Rx C 5 X
Generic name:
pregabalin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
phenytoin Off-label 5.0 3 reviews for phenytoin to treat Peripheral Neuropathy
Rx D N X
Generic name:
phenytoin systemic
Drug class:
hydantoin anticonvulsants, group I antiarrhythmics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
levocarnitine Off-label 8.3 4 reviews for levocarnitine to treat Peripheral Neuropathy
Rx B N
Generic name:
levocarnitine systemic
Brand names:
L-Carnitine, Carnitor, Carnitor SF
Drug class:
nutraceutical products
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
L-Carnitine Off-label 8.3 4 reviews for L-Carnitine to treat Peripheral Neuropathy
Rx B N
Generic name:
levocarnitine systemic
Drug class:
nutraceutical products
For consumers:
dosage, interactions, side effects
For professionals:
Natural Product Monographs
Off-label:
Yes
gabapentin Off-label 6.3 195 reviews for gabapentin to treat Peripheral Neuropathy
Rx C N X
Generic name:
gabapentin systemic
Drug class:
gamma-aminobutyric acid analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
duloxetine Off-label 6.0 48 reviews for duloxetine to treat Peripheral Neuropathy
Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Carnitor SF Off-label Rate Add review
Rx B N
Generic name:
levocarnitine systemic
Drug class:
nutraceutical products
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Carnitor Off-label Rate Add review
Rx B N
Generic name:
levocarnitine systemic
Drug class:
nutraceutical products
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
carbamazepine Off-label 6.8 10 reviews for carbamazepine to treat Peripheral Neuropathy
Rx D N X
Generic name:
carbamazepine systemic
Drug class:
dibenzazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
capsaicin Off-label 5.9 13 reviews for capsaicin to treat Peripheral Neuropathy
Rx/OTC B N
Generic name:
capsaicin topical
Brand name:
Qutenza
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes

Frequently asked questions

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Topics under Peripheral Neuropathy

Alternative treatments for Peripheral Neuropathy

The following products are considered to be alternative treatments or natural remedies for Peripheral Neuropathy. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Peripheral Neuropathy.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.