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Medications for Obsessive Compulsive Disorder

Other names: Obsessive Compulsive Neurosis; OCD

An anxiety disorder characterised by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behaviour which the individual generally recognises as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Drugs used to treat Obsessive Compulsive Disorder

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Zoloft 8.0 161 reviews for Zoloft to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
sertraline systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ziprasidone Off-label 3.7 3 reviews for ziprasidone to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
ziprasidone systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
vilazodone Off-label 4.2 13 reviews for vilazodone to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
vilazodone systemic
Drug class:
miscellaneous antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
venlafaxine Off-label 7.5 43 reviews for venlafaxine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
venlafaxine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
tramadol Off-label 9.7 3 reviews for tramadol to treat Obsessive Compulsive Disorder
Rx C 4 X
Generic name:
tramadol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
sertraline 7.9 286 reviews for sertraline to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
sertraline systemic
Brand name:
Zoloft
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
riluzole Off-label 8.5 4 reviews for riluzole to treat Obsessive Compulsive Disorder
Rx C N
Generic name:
riluzole systemic
Drug class:
miscellaneous central nervous system agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
quetiapine Off-label 8.5 48 reviews for quetiapine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
quetiapine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Prozac 8.1 120 reviews for Prozac to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
fluoxetine systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Paxil 7.4 33 reviews for Paxil to treat Obsessive Compulsive Disorder
Rx D N X
Generic name:
paroxetine systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
paroxetine 7.2 48 reviews for paroxetine to treat Obsessive Compulsive Disorder
Rx D N X
Generic name:
paroxetine systemic
Brand name:
Paxil
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ondansetron Off-label Rate Add review
Rx B N
Generic name:
ondansetron systemic
Drug class:
5HT3 receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
olanzapine Off-label 7.1 21 reviews for olanzapine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
olanzapine systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
mirtazapine Off-label 6.7 28 reviews for mirtazapine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
mirtazapine systemic
Drug class:
tetracyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
fluvoxamine 7.2 206 reviews for fluvoxamine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
fluvoxamine systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fluoxetine 7.9 183 reviews for fluoxetine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
fluoxetine systemic
Brand name:
Prozac
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
escitalopram Off-label 8.3 130 reviews for escitalopram to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
escitalopram systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
clonazepam Off-label 9.3 20 reviews for clonazepam to treat Obsessive Compulsive Disorder
Rx D 4 X
Generic name:
clonazepam systemic
Drug class:
benzodiazepines, benzodiazepine anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
clomipramine 8.0 189 reviews for clomipramine to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
clomipramine systemic
Brand name:
Anafranil
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
citalopram Off-label 7.5 44 reviews for citalopram to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
citalopram systemic
Drug class:
selective serotonin reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
aripiprazole Off-label 7.0 36 reviews for aripiprazole to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
aripiprazole systemic
Drug class:
atypical antipsychotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Anafranil 7.9 72 reviews for Anafranil to treat Obsessive Compulsive Disorder
Rx C N X
Generic name:
clomipramine systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

View more FAQ

Topics under Obsessive Compulsive Disorder

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.