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Medications for Narcolepsy

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Lumryz 10 1 review for Lumryz to treat Narcolepsy
Rx B 3 X
Generic name:
sodium oxybate systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zenzedi 9.5 2 reviews for Zenzedi to treat Narcolepsy
Rx C 2 X
Generic name:
dextroamphetamine systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
desvenlafaxine Off-label 9.0 1 review for desvenlafaxine to treat Narcolepsy
Rx C N X
Generic name:
desvenlafaxine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Methylin ER 9.0 1 review for Methylin ER to treat Narcolepsy
Rx C 2 X
Generic name:
methylphenidate systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
lisdexamfetamine Off-label 8.8 11 reviews for lisdexamfetamine to treat Narcolepsy
Rx C 2 X
Generic name:
lisdexamfetamine systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
dextroamphetamine 8.7 35 reviews for dextroamphetamine to treat Narcolepsy
Rx C 2 X
Generic name:
dextroamphetamine systemic
Brand names:
Dexedrine, Zenzedi, ProCentra
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Methylin 8.6 5 reviews for Methylin to treat Narcolepsy
Rx C 2 X
Generic name:
methylphenidate systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dexedrine 8.5 16 reviews for Dexedrine to treat Narcolepsy
Rx C 2 X
Generic name:
dextroamphetamine systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ephedrine Off-label 8.5 2 reviews for ephedrine to treat Narcolepsy
Rx/OTC C N
Generic name:
ephedrine systemic
Drug class:
vasopressors, decongestants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Adderall 8.2 68 reviews for Adderall to treat Narcolepsy
Rx C 2 X
Generic name:
amphetamine / dextroamphetamine systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
amphetamine / dextroamphetamine 8.1 96 reviews for amphetamine / dextroamphetamine to treat Narcolepsy
Rx C 2 X
Generic name:
amphetamine / dextroamphetamine systemic
Brand name:
Adderall
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate 8.1 9 reviews for calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate to treat Narcolepsy
Rx 3 X
Generic name:
calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate systemic
Brand name:
Xywav
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
Xywav 8.1 9 reviews for Xywav to treat Narcolepsy
Rx 3 X
Generic name:
calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sodium oxybate 7.7 106 reviews for sodium oxybate to treat Narcolepsy
Rx B 3 X
Generic name:
sodium oxybate systemic
Brand names:
Xyrem, Lumryz
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xyrem 7.7 96 reviews for Xyrem to treat Narcolepsy
Rx B 3 X
Generic name:
sodium oxybate systemic
Drug class:
miscellaneous anxiolytics, sedatives and hypnotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
methylphenidate 7.4 65 reviews for methylphenidate to treat Narcolepsy
Rx C 2 X
Generic name:
methylphenidate systemic
Brand names:
Ritalin, Concerta, Methylin, Methylin ER
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Concerta 7.2 14 reviews for Concerta to treat Narcolepsy
Rx C 2 X
Generic name:
methylphenidate systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
amphetamine 7.0 2 reviews for amphetamine to treat Narcolepsy
Rx C 2 X
Generic name:
amphetamine systemic
Brand name:
Evekeo
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ritalin 7.0 33 reviews for Ritalin to treat Narcolepsy
Rx C 2 X
Generic name:
methylphenidate systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Provigil 6.6 94 reviews for Provigil to treat Narcolepsy
Rx C 4
Generic name:
modafinil systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
modafinil 6.5 153 reviews for modafinil to treat Narcolepsy
Rx C 4
Generic name:
modafinil systemic
Brand name:
Provigil
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Nuvigil 6.5 88 reviews for Nuvigil to treat Narcolepsy
Rx C 4
Generic name:
armodafinil systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
armodafinil 6.2 128 reviews for armodafinil to treat Narcolepsy
Rx C 4
Generic name:
armodafinil systemic
Brand name:
Nuvigil
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Wakix 5.6 21 reviews for Wakix to treat Narcolepsy
Rx N
Generic name:
pitolisant systemic
Drug class:
CNS stimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
solriamfetol 5.3 49 reviews for solriamfetol to treat Narcolepsy
Rx 4
Generic name:
solriamfetol systemic
Brand name:
Sunosi
Drug class:
miscellaneous central nervous system agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

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Topics under Narcolepsy

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Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.