Skip to Content

User Reviews for Vortioxetine

Also known as: Brintellix, Trintellix

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Vortioxetine.

Filter by:

User Ratings

10
   
16%(40)
9
   
20%(52)
8
   
17%(45)
7
   
7%(18)
6
   
5%(12)
5
   
6%(15)
4
   
4%(9)
3
   
7%(18)
2
   
8%(20)
1
   
14%(37)

Vortioxetine Rating Summary

6.3/10 Average Rating

266 Ratings with 275 User Reviews

What next?Compare all 223 medications used in the treatment of Depression.

Reviews for Vortioxetine to treat Depression

Sort by:

"Been on trintelex for about 3 months now. Have never taken anything for anxiety or depression. I starts at 10 mg and saw no change and now I'm on 20 mg and feel amazing! I'm not as Fearful anymore and when I rarely do have a panic attack , it is easier to cope with and I can pull myself out of it easier. Been trying new things and lovig life! Side effects have been minimal, mild nausea the first few weeks. Very tired I've noticed but it's all worth it. I forgot to take It over a weekend once and had terrible anxiety and depression worse then before but went away after taking the medication for 2 days in a row. I could not be happy without this medication."

   
9.0

JanuaryRoses May 28, 2016

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I was on Brintellix for a short time while trying to transition from Lexapro. Unfortunately it was just not the drug for me. I had terrible nausea that never went away, as well as vomiting. Brintellix didn't really do anything for my anxiety, either, and I definitely noticed symptoms of that again. By the time I stopped taking it, my depression was actually worse, but I think it didn't help that I was feeling so bad physically. If you already have digestive issues, this might not be the med for you."

   
2.0

Digestive side effects May 27, 2016

1 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Mild nausea when going up to 20mg for first few days - increased sex drive - no side effects which is a miracle being that every other med I've taken has given me every possible side effect. Very satisfied!"

   
8.0

HappyDayzRHere2stat May 24, 2016

6 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I was about to give up on this med because of the awful nausea it caused but for the past three days I have been swollowing it down with ginger ale and the nausea has miraculously disapeared."

   
5.0

Bbb12345 May 18, 2016

6 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "My doctor noticed that the other medication that I was on was not working well and had me start Brintellix (10 mg per day) from samples he had. There was a direct transition from the other medicine to this one - no tapering off or anything like that. After just a few days, the medicine and I apparently agreed that it would work for me. The side effects that I have are mild headache and sometimes loose stool - to be polite. I'm excited about this one. Big differences in a short time."

   
8.0

Happi-er (taken for less than 1 month) May 17, 2016

8 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "At first it kept me awake, but that went away in like a week or two. By the 3rd month I can say this is the best stuff I've been in and can laugh again and not hate the world. I have severe depression, anxiety with PTSD."

   
10

Ripleysmom May 9, 2016

24 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Tried to take months earlier but stopped due to nausea and diarrhea. Gave it another try today....bad idea. Very sick within 1 hour of taking. Horrific headache followed by vomitting everything in my stomach."

   
1.0

Bayoumom (taken for less than 1 month) May 5, 2016

13 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "When I started having Brintellix 10mg, nausea and itching nearly made me discontinue, but as my doc added Atarax 25mg (hydroxyzine) those nasty side effects disappeared completely. I think I am pretty satisfied with the drug, since I can tolerate it better than SSRI's or SNRI's, only minus is the higher cost compared to the older drugs."

   
9.0

Jonas Richter May 1, 2016

15 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"Just took my first dose today.I have done through many antidepressants so I hope this one works. Anyone tell me how long before I start feeling better?"

ontnurse2 (taken for less than 1 month) April 29, 2016

0 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Mild to moderate nausea, nothing too bad. Really good effect on my general mental state. Feel so much better. A big help in combination with therapy."

ScoobyDoo91 April 26, 2016

18 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I'm on brintellix for month and a half now. I've also been using valdoxan for three months, but it didn't give any significant effect so I've started taking brintellix 10 mg and after three weeks I felt an effect. It seems like I'm getting better every day. My mood, energy level and motivation have increased, my suicidal thoughts are gone and I am finally able to cope with my every day responsibilities."

   
10

Cristaliu April 24, 2016

40 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Suffer from anxiety depression, which I had no idea why everything in life irritated me. Started off w/5mg and noticed in the morning that I was completely calm and not yelling at my kids. I no longer have road rage so that is a good thing for all stupid drivers :)"

   
10

Monis17 April 19, 2016

47 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"Started 2 weeks on 5 mgs and then 6 weeks on 10mgs. The only positive was that I stopped crying every day(was dealing with benzo withdrawal). Had headaches, diarrhea, constipation, worsening depression(at 5 weeks I laid in bed for 5 days, didn't want to eat/sleep/cook/clean - my initial problem was anxiety, not so much depression, med made me way more depressed), many migraine auras, pressure in my head, ear ringing, fear, worsening anxiety, only felt better once I cut back to 5mgs, then off 2 weeks now. Still have some mounting anxiety, but hopefully will subside or I may try low dose of Amitriptyline. I am sensitive to antidepressants, they make my anxiety worse."

   
1.0

Anxiousgal68 (taken for 1 to 6 months) April 17, 2016

1 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Took 10mg samples in the AM, nausea and dizziness big problem 3rd and 4th day. Stopped for 2 days. Then took 1/2 pill in the evening around 8PM. A little nausea, sleep was affected but adjusting. But I believe it is what I need. I left the house 3 times on the weekend, answered my phone, went into 6 stores and most important, while home didn't lay in bed."

   
8.0

Cward10 April 16, 2016

50 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Been on Brintellix for 1 month as an add-on to my longtime SSRI, which had become much less effective in recent months. I felt better in 6 days after starting Brintellix: depression and anger lifted, I began to feel like doing this again. Every day is better and better."

   
9.0

Workingwell (taken for less than 1 month) April 16, 2016

37 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "18, Female. Been taking this on and off for 8 months now. I cannot take it everyday even if I am prescribed to do so since the side effects are really taking a toll on my ability to function in everyday life. It made my depression worse. I can barely get out of bed due to fatigue from nausea and vomiting. And everytime I take this it is like the headache will stay with you 24/7 that it really becomes intolerable and frustrating. My doctor won't let me switch to another medication and she's really pushing this for me and it is so cruel since I feel so weak and I don't want to continue anymore. Taking it makes me want to die."

   
1.0

Alleria April 13, 2016

28 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Female, 46yrs, depression for ~10yrs. I went on Trintellix 10mg at the end of January and from the very first day, I've been dizzy and nauseous. Yesterday, the nausea was at its worst. I also take Vyvanse 50mg for ADD and hydrochlorothiazide 12.5mg for high blood pressure plus another BP med. Shortly after going on Trintellix, I started to develop bruising on my upper thighs as well as itching. I think as I scratch, I end up bruising and it looks awful. I contacted my doc and am still waiting for a reply. Hopefully, I'll be taken off of it and will go back to Cipralex and Wellbutrin even though my libido has improved somewhat. At least I'm not crying at the drop of a dime as happens when I don't take any meds at all. Good luck everyone!"

   
2.0

Grade2Teacher (taken for 1 to 6 months) April 12, 2016

17 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Horrible drug. I have switched from effexor to this because of sexual disfunction and lack of sex drive. This has improved those sex issues but the other effects are worst. I have been more irritable,angry and not happy. Small things easily make me angry inside. I notice my blood pressure higher maybe because of the drug or just being more angry inside and out. Dont take this medication. There are other better meds that are out there. I'll go back to effexor and taking viagra to become the happy champ lol."

   
1.0

italiantribe (taken for less than 1 month) April 9, 2016

14 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I started out on 5mg and was okay. Was a little nausea at first...but needed to increase my dose due to the seasons. When I got put on 10mg.... the vomiting and sickness really kicked in. Almost every time I take it.... I vomit 10 minutes later. I'm also way more tired than I ever have been. I feel emotionless, and like I could sleep all day everyday. My mind feels Ike I can't think sometimes. The 5mg never did any of this. All this started when I increased my dose."

   
3.0

CMGriffy2016 April 7, 2016

21 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Mid 30's with depression for over 4 years. Was on Lexapro 10mg then 20mg for a lil while, but it wasn't enough and the psych doc wouldn't listen to me or change my meds. So after 2 years of dealing with him I switched to another psych doc who actually listened to me. First she added Wellbutrin 150 then 300 XL, it wasn't such a great difference so she switched me to Brintellix after insurance approval. She started me out at 5mg then titrated up to 10mg then 20mg. The first few days were the worst with side effects, but mine were nausea and diarrhea, that only I got better in time. The feeling after being on this medication was great! I felt more like my old self again, happier, more motivated, less isolation, and got my sex drive back"

   
8.0

Juliez2 March 23, 2016

70 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "First few weeks were weakness irritability. Now on month two and stopping because of cost ($700 and insurance won't cover it) and major irritability and weight gain. Also still depressed and anxious."

   
4.0

Opinion (taken for 1 to 6 months) March 21, 2016

27 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I have been on Brintellix for 8 months. It has been life changing for me. I feel it literally saved my life. I have been on more medicines than I can count over the past 15 yrs. I did have nausea pretty bad for the first couple weeks on Brintellix but taking the medicine at night with crackers and Sprite it was much better after about 2 weeks. Now here is the hopeless part... I have to go off the medicine due to severe side effects that I do not see others reporting. About 6 months into taking Brintellix (4 months on 10 mg and 5 months on 20 mg)I got severely sick with unexplainable internal bleeding and severe gastro problems.Thousands of dollars on medical testing and nothing found.2 days off better but mental disaster.terrible withdrawal"

   
2.0

Daisy987 March 20, 2016

45 users found this comment helpful. Did you?   Yes   No Report as inappropriate

"I have been taking Trintellix 10mg for about 5-6 months. It was added to a low dose of Pristiq I was already taking. My mood was down quite a bit, and Pdoc added it. All I can say is my results are outstanding. It's by far the best med I've ever been on over the past 20 years. No side effects, it raised my mood, motivated me without making me manic or hypomanic and sharpened my mental faculties tremendously. It allows me to consistently function at a very high level. For cost, I'm on a compassionate care program, and it doesn't cost me anything right now. But even if I had to pay, it's well worth it for me."

   
10

RunRiver (taken for 1 to 6 months) March 20, 2016

9 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "I'm a junior in high school and I've been struggling with depression, I've been on atleast 4 different medicines already and this one seemed to be good. But recently I had to be taken out of school for extreme nausea and vomiting, and it's only been a few weeks."

   
5.0

Random high school teenager March 17, 2016

23 users found this comment helpful. Did you?   Yes   No Report as inappropriate

Brintellix (vortioxetine): "Higher dose causes more nausea for me. Moderate depression relief."

   
7.0

JjJD March 16, 2016

21 users found this comment helpful. Did you?   Yes   No Report as inappropriate
Page 1 2 3 4 5 6 7 8 9 10 11 Next
Hide