User Reviews for Vortioxetine

Also known as: Brintellix

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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10
   
15%(4)
9
   
18%(5)
8
   
29%(8)
7
   
4%(1)
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8%(2)
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15%(4)
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Vortioxetine review summary

6.9/10 Average Rating

28 Ratings with 26 User Reviews

Compare all 137 medications used in the treatment of Depression.

Reviews for Vortioxetine to treat Depression

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Review by Webwiz (taken for 1 to 6 months):

User Rating:  
   
1.0

Brintellix (vortioxetine): I took 10 mg for a few days but became very uncomfortably manic. So I started to cut the pill and it ends up that I am taking 20 mg over 3 days. This is the end of the 6th week. I have had chronic clinical depression for 27 years. I am taking this with 225 mg of Buproprion a day and 50 mg of Fluvoximine. I experience no improvement and have had more thoughts of suicide in a long time. I see the doc in two weeks. If it is not noticeable by that time, 8 weeks, out it goes.

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July 18, 2014 4:12 PM

Review by nursecrybaby:

User Rating:  
   
8.0

Brintellix (vortioxetine): I have only been on this medicine for 1 week. Still on 10mg. Went cold turkey off 30mg of Lexapro. Not seeing a big difference yet in the depression but after going off the high dose of Lexapro I expect to not see a difference in my depression yet. What I wanted to share was that I have itching skin. I just want to scratch and scratch. I'm sure it will go away. I'm hoping to have wonderful news on my next post regarding the depression and hopefully some weight loss too.

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July 16, 2014 5:23 AM

Review by Girlfriend in a Coma (taken for less than 1 month):

Brintellix (vortioxetine): I started taking it on Tuesday morning and by that evening started with some nausea. It got worse Wednesday, to the point where I had to leave work. Horrible headache, too. Today (Thursday) the nausea is somewhat better but the headache remains. Called my doc and she said nausea is a huge side effect, unfortunately. It may take up to 2 weeks to fully subside, but to stick with it. Try taking it at night, cutting the dose in half (I'm on 10mg), or taking with food. This is a very new medicine so I hope this helps others in their first couple weeks.

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July 3, 2014 11:22 AM

Review by Guenda (taken for 1 to 6 months):

User Rating:  
   
10

Brintellix (vortioxetine): A total turn around! I feel like a new person. It's been a long road. I lost my husband of 36yrs, 3 1/2 yrs ago. I had just been surviving; not living. My dr. gave me samples and explained how this medicine works.

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June 11, 2014 5:54 PM

Review by AJF:

User Rating:  
   
10

Brintellix (vortioxetine): I'll be trying Brintellix starting tomorrow, so I haven't rated it for "real" for that reason - I had to rate it in order to post this pre-beginning review. I read the other reviews and I'll share my experience with it. Like many others, I've taken other anti-depressants (since diagnosed in 1997), which are the following: Prozac, Wellbutrin, Lexapro, Zoloft, & Effexor (I STRONGLY urge everyone to think twice before taking Effexor - it's the only anti-depressant that had major, long-term withdrawals and was ineffective as well). I've also been taking Xanax 3 times a day for 17 years, and it's been a Godsend (not one panic attack since the first day I took it) and has a low impact on the body. I'm interested to see if this is helpful.

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May 29, 2014 6:47 PM

Review by Kittykat2014:

User Rating:  
   
4.0

Brintellix (vortioxetine): I'm extremely sensitive to the side effects of these medicines. Remeron is the only one I can tolerate (and it doesn't give me enough relief by itself). Brintellix's side effects reminded me of Pristiq's--falling asleep during the day, not able to sleep at night but it worked on my Interstitial Cystitis and it reduced my appetite, so I'm going to give it a longer trial in the summer when school is out and I'm not working.

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May 24, 2014 10:51 PM

Review by tambogal:

User Rating:  
   
9.0

Brintellix (vortioxetine): This has worked the best for me thus far. I have been on several SEVERAL anti-depressants and by far this has been better with very little side effects. Nausea has been the only downside at this point. I missed two days due to my pharmacy being closed and didn't have the "brain zaps" after missing. Big plus in my book.

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May 19, 2014 1:54 PM

Review by Gmh77 (taken for 1 to 6 months):

User Rating:  
   
6.0

I've been on Brintellix 10mg for 6 weeks. Seems to be helping some with depression, not as much with anxiety but still have a happier mood and more get up and go then before. I do feel a little more tired then normal but the worst side effect is I have no sex drive. I didn't have much of one before taking it but hoped having a happier mood would help that but scared it made it worse. My dr wants to see me back about doing an increase but worried it will make my already very low sex drive worse unless it makes me feel happier and helps? Just not sure my low sex drive is still from unhappiness and anxiety or the Brintellix? Unsure of what to do but none of the other SSRI's have worked for me in the past.

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May 8, 2014 8:32 AM

Review by spoookee (taken for 1 to 6 months):

User Rating:  
   
9.0

Brintellix (vortioxetine): Generally speaking, I don't like anti-depressants. I've taken Zoloft, Paxil, Effexor (which was the horrible one for *me*), Lexapro, Prozac...seems like I'm forgetting one. They've never made me feel "better" or "happy," just "numb" and "flat." With Brintellix, I started off at 10mg for 6 weeks. I go for my checkup tomorrow and will be increasing to 20mgs. YES, I DID get nausea in the mornings for a couple of hours after I'd taken it. Taking it with food helped. That is a side effect that, for me anyway, went away within a couple of weeks. I expect the same with increasing to 20mgs, but I think it's worth it in the long run. I actually feel HAPPIER! More energetic, want to do things, etc. Has been miracle so far for me.

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April 30, 2014 2:57 PM

Review by MP2014:

User Rating:  
   
8.0

Brintellix (vortioxetine): I've tried so many antidepressants but this one has been the best. I was on 10mg for a month and just had my dosage increased to 20 mg, two days ago. I do feel sick; nausea and a little disoriented but those are bearable side effects to me. I have had energy, better concentration but the biggest thing I love about this antidepressant is that I have my sex drive back. My libido wasn't affected like it has been in the past with other meds; I've actually had increased sex drive. So far I feel "okay" but hopefully since 20mg is the therapeutic dose, that I feel more "content" or "happy" with my life soon.

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April 3, 2014 9:09 PM

Review by Cattinni (taken for less than 1 month):

User Rating:  
   
4.0

Brintellix (vortioxetine): I am very medication resistant and was really hoping this medicine would turn it around. Started at 5 mgs and had blinding headaches and stabbing pain in my stomach. Day five, I had a huge panic attack and confusion. Gave me the kind of out of it feeling that I had with Effexor.

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April 2, 2014 3:20 PM

Review by Tropic (taken for less than 1 month):

User Rating:  
   
8.0

Brintellix (vortioxetine): No side effects, a lot of sleeping, but a slight improvement of mood. 2 weeks so far.

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March 31, 2014 6:54 PM

Review by Copenhagun (taken for 1 to 6 months):

User Rating:  
   
10

Brintellix (vortioxetine): I've been suffering from major depression since I was a teen. I've had issues with panic attacks, severe anxiety, obsessive compulsive disorder, and just about everything else. For years I've been on Lexapro because it's the only medication that would work for me. The side effects of Lexapro however were horrendous! The side effects outweighed the benefits. After a few months of discussing it, my doc switched me to Brintellix. I have done a 180! I feel so much better that it scares me! I haven't felt this good in so long that I forget how to act. I'd say it's a miracle., but I know it's no miracle.. it's science! After a lifetime of depression, I'm excited for the future.

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March 23, 2014 9:35 AM

Review by joyjack31:

User Rating:  
   
2.0

Brintellix (vortioxetine): started on 10mg for 1 month had nausea and dry mouth, but nausea started to go away, still having depression and some anxiety. then doc went up to 20mg. I been on 20mg for almost two weeks. I been having nausea all day, severe acid reflux, severe indigestion and really bad upset stomach. not sure if this is related but if it is, I cant wait to stop this medicine.

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March 20, 2014 6:04 PM

Review by mgm30:

User Rating:  
   
6.0

Brintellix (vortioxetine): I am taking 10 mg for 3 weeks now. After the first week I've started to feel a little bit better side effects dry mouth, I was not eating that much which is good because I am over weight but after the 3 week started to feel again depressed so it means that so far is not helping me, I went to the doctor today. I will increase starting tomorrow 15 mg and lets see how it goes...I will keep you posted.

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March 18, 2014 6:54 PM

Review by AnonMom (taken for 1 to 6 months):

User Rating:  
   
4.0

Brintellix (vortioxetine): Past experience taking medicines that did work (Celexa, Wellbutrin), 1-2 years later they seemed to stop working (weepy, sad, never wanted to get out of bed, no desire to do anything, flash backs of a traumatic event, constantly dwelling on negative past experiences, etc.). 10mg Brintellix prescribed (1/10/14) while weaning off Wellbutrin. Not so weepy, but was still sad, had no motivation to get out of bed or do anything. Increase to 20 mg (1/28/14), felt like I was going "downhill" fast: even sadder and weepier, etc. Told it may have been too much at once, so was told to take 1/2 dose one day, full dose the next (2/15/14). Still not feeling as well as I thought I should. Increase to 20 mg Blood Pressure went up from 110/68 to 124/72.

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March 11, 2014 12:00 PM

Review by lost in Ohio (taken for less than 1 month):

User Rating:  
   
8.0

Brintellix (vortioxetine): I've been on 10mg Brintellix for a week now. The first day I took it within 30 minutes I was sick. Which I could afford to lose a few pounds so I guess I won't complain about that. I've been extremely tired since taking this medicine. However my mood does seem brighter while I'm awake. I also take Trileptol, Tramadol, Norco, gabapentin, and two inhalers. I'm 33 and have some health issues and so far the medicine seems to be helping. I just hope it stays this way. Good luck to everyone.

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March 8, 2014 9:45 AM

Review by Anonymous (taken for 1 to 6 months):

User Rating:  
   
3.0

Brintellix (vortioxetine): I have been on Brintellix for nearly six weeks. I experienced severe nausea for the first 10 days but thankfully it subsided after that time. The medicine has mellowed me out but I still feel very zoned out, tired and listless. I don't have a "joy" for life with this medicine that I experienced on another antidepressant in the past. My major concern is an increase in blood pressure. I am an extremely healthy 35 year old female whose blood pressure has ALWAYS been 110/70. Since starting this medication, my blood pressure has gone from 110/70 to 120/82, then 139 over 74 and now 149 over 80. Nothing has changed in the past six weeks other than the addition of the medicine. I'm hoping to find something that is going to work soon.

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March 5, 2014 4:07 PM

Review by Sennerin (taken for less than 1 month):

User Rating:  
   
9.0

Brintellix (vortioxetine): I have been taken 10 mg for 3 weeks. I have taken other anti depressants before with very little to no help. With this one I feel a lot better, I have more energy, I can focus and concentrate better. My mind is clearer than it has been for a long time and I am happier. So far I have no side effects besides I am a little constipated.

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February 28, 2014 12:08 PM

Review by MoodyMama67 (taken for less than 1 month):

User Rating:  
   
8.0

Brintellix (vortioxetine): I have been on Brintellix 10 mg and increased to 20 mg on 02/19/2014. I have experienced dry mouth, dizziness, forgetfulness, no desire to eat, weight loss of 11 lbs in 10 days, which is good considering I'm overweight, this can't be a bad thing, and wake up often, however, I am in a happier mood and not so stressed out. I have been on Brintellix for a total of 11 days. Hope the yucky side effects go away soon. I have tried almost everything else and nothing has worked mood wise for me as good as this is.

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February 20, 2014 2:11 PM

Review by desss:

User Rating:  
   
9.0

Brintellix (vortioxetine): I have been taking 20 mg for about 1 month. I feel awesome. I have taken everything you can imagine and no success. I take this along with 3 other medicines. I have energy and no side effects. I couldn't be happier. I hope it stays this way. I was at a horrible place and now have hope.

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February 15, 2014 6:18 PM

Review by LaCristal:

User Rating:  
   
9.0

Brintellix (vortioxetine): I'm on week two at just 5mg a day. So far no major side effects, only some nausea that comes about an hour or two after taking the pill. I'm hoping this is the one for me.

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February 9, 2014 4:38 PM

Review by SALosangeles (taken for 1 to 6 months):

User Rating:  
   
8.0

Brintellix (vortioxetine): I have been on 10mg it for 8 weeks and it works well for me. I did not want to go up to 20mg but I was going through some ups and downs so my Dr. recommended I go up to 20mg. This is my 4 day on it and seems to be working better. I did not have any sexual side effects or notifiable weight gain but I do seem to have some tingling sensation in my head. This is my first time on Antidepressants.

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February 3, 2014 4:02 PM

Review by sickofbeingsick31 (taken for less than 1 month):

User Rating:  
   
8.0

I have been taking 5mg of Brintellix for a week now. So far, I think it has greatly helped my depression. Unfortunately, it seems to be making me very, very sleepy all the time and it has caused a bit of nausea. I am hoping the side effects will wane over the next couple of weeks. There is some great news besides it helping with my major depression- I have not experienced any sexual side effects like I did on Zoloft.

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January 23, 2014 7:21 PM

Review by frannigan:

User Rating:  
   
2.0

Brintellix (vortioxetine): I was so hopeful for this to work but I had an allergic reaction after 18 days, face tingling, agitation, chills, fever. Had to discontinue and now feel terrible withdrawals fever, chills after stopping. I hope others have phenomenal success though. I'm just sensitive to medicines.

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January 8, 2014 12:29 PM

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