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User Reviews for Venlafaxine

Also known as: Effexor, Effexor XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Venlafaxine Rating Summary

7.0/10 Average Rating

47 Ratings with 33 User Reviews

What next?Compare all 36 medications used in the treatment of Fibromyalgia.

Reviews for Venlafaxine to treat Fibromyalgia

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"I've been taking antidepressants for about 15 years, due to panic attacks, general anxiety, and situational depression, and they have worked well. Additionally, for 10 years I have had very severe leg pain, seeming to be sciatica/nerve pain and muscle pain, from hips to feet. I was told by two orthopedists that, "You're just old (59) so live with it." It's been only a month since I changed to SNRIs--namely Venlafaxine--and since the very first day, I have been pain free. I can walk again with long strides and quickly. I can stand for long periods. I can take hikes. I hadn't been able to do that for 10 years.. My life is no longer dictated by how much pain I can endure. I don't know how it works, but I wish I'd known about it years ago."

   
10

Carol D. (taken for 1 to 6 months) April 17, 2016

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"I have had fibromyalgia since I was 10 years old have been on every medication doctors can think of. Iam now in my 40s and my fibromyalgia has got worse of time, I was on Cymbalta for years but it stopped working so yesterday my doctor prescribed Effexor XR I took it and this mornings I was not stiff, not moody and slept good last night , I am hoping this will help me in long term."

   
10

Toughcowgirl February 24, 2016

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"Hi I was on cymbalta for 6 weeks gained 17 lbs. I started back to Effexor. Have lost 4 lbs in a week of coming off cymbalta and going back on Effexor. Cymbalta made me retain fluid. I was miserable on cymbalta. Rheumatologist wanted me to try cymbalta so I gave it a try for fibromyalgia I went through a little electric feeling for about 3 days coming off cymbalta. Can anyone tell me what else is good to take for the fibromyalgia pain. Effexor seems to help some , but still having some pain."

   
9.0

Anonymous January 20, 2016

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"You can treat Effexor (and Paxil) withdrawal by using one dose of a very long acting SSRI such as Prozac. (Prozac is so long lasting that one dose can be taken weekly.) Going thru the electrical zapping sensations and disconnected head feeling is very disturbing and best avoided."

   
9.0

Treating Effexor withdrawal (taken for 2 to 5 years) December 27, 2015

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"I have had fibro for 18 years and have been on many medications. Being put on Effexor XR over a year ago I have tolerated it well .. Maintained a healthy weight and it takes the pain from a 10 down to 2-3. My only complaint is that I have always had a sharp mind and I notice that I feel lost sometimes in what I'm doing even in my own home .. Very loopey. I'm 43 years old and take this along with 50 mg x2 of Tramadol every day. I would recommend it if you have fibromyalgia. It's worked better than all other snris or ssris out there."

   
9.0

MetroFarms December 21, 2015

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"Effexor XR has helped a lot and I've stayed at 75 mg. but others may need more. Also, a few people have mentioned that they fear getting off of it because of withdrawal. Your doctor can help if you ever need to get off. I believe the technical term is "Effexor - Prozac bridge." In other words, you take the longer acting medication (like Prozac) to counteract the short half-life of Effexor. A doctor could explain it better than I can, but hopefully that will alleviate any concerns."

   
8.0

Gabriellakw September 25, 2015

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"In the last year I had a diagnosis of myofacial pain syndrome, now its fibromyalgia. I am not convinced HMO doctor knows. Other than pain I have a variety of other symptoms, just none are mental health related. I have been told to take up to 225mg but now reduced in last week to 75 mg before I read of the withdrawal symptoms. So far I am fine but am concerned now that I might be overwhelmed reducing under 75 mg. Doing this on own since doctor said it is up to me."

   
5.0

Annesa (taken for 6 months to 1 year) June 21, 2015

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"My practitioner was not allowed by the HMO to diagnose or treat fibromyalgia. She had to wait until my pain, fatigue and brain fog threatened my job and stressed me to the point of flunking the mental health quiz they give us. After the initial side effects, which I decribe as "itchy blood", I was more mobile and clear-headed, sleeping and waking on a normal schedule. I've never done that before. The withdrawals are weird, so I keep the old bottle handy from when I switched to time-release. I didn't realize how much pain I had been trying to cope with until the first time I ran out."

   
8.0

Bossmom June 9, 2015

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"I have cPTSD, serious depression, anxiety and I also suffer from Fibromyalgia. I will never get off of Effexor, because it works and the withdrawal symptoms scare me to death. I would only suggest Effexor as a last resort and only for someone with long term issues because of the withdrawal problems. Effexor is a lifetime commitment but it works so that's ok with me. I did try other medications and honestly, the one thing I have learned to test if an antidepressant is going to work is if after a week of taking it whether there is sexual dysfunction or not. I wish it helped me more with the Fibro but it is so worth it for the anti-anxiety. I can buy 90 days of generic at Costco for under $40 and that is cheaper than my insurance copays"

   
9.0

Your Queen May 20, 2015

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"I was so surprised...within 4-5 days the major discomfort from fibromyalgia was nearly gone. I could sleep more comfortably and did not feel like the princess and the pea when I laid down. I hope it continues."

   
9.0

Lynn2713 October 4, 2014

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"I love it. I get dizzy and almost black out when I hop up. So I learned to get up slow. My pain has turned dull now instead of sharp and menacing like it's been for almost 5 yrs. Taking this with Oxycodone and Robaxin helps me get through each day. Still not well enough where I can exercise due to horrible muscle inflammation. Started on the 25mg...moved to 75mg...now I'm taking the 150mg XR and I can say that I think I should stay here."

   
7.0

That Lupus Guy (taken for 1 to 6 months) August 17, 2014

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"I have had fibromyalgia symptoms for over 2 years now, muscle cramps that stay in a locked position for days. I am in constant pain. I have only been on venlafaxine for not quite a week and have to admit it has controlled the pain to a dull ache instead of the throbbing pain before. My doctor started me out on 37.5 mgs and after 4 days we increased it to 75 mgs. I seem to tolerate this dosage well. I am happy with the benefit of helping my anxiety level. I see hope at the end of the pain tunnel."

   
7.0

Juleen August 9, 2014

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"I started out on 37.5mg and moved up to 75mg. I feel great! I have gone back to work and I'm enjoying life again. I went from barely being able to move or being touched to almost normal. Minor flares but it is tolerable."

   
10

Anonymous (taken for 6 months to 1 year) January 2, 2014

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"I take 4-75 mg pills 2x a day. So I am on the maximum dosage. It has does wonders for me. Through my Doctor's office I get a discount on medication so this is super cheap for me since I don't have insurance at this moment. I was on Cymbalta and it worked exactly the same but was WAY to pricey."

   
10

Jte1311 (taken for 2 to 5 years) December 18, 2013

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Effexor (venlafaxine): "They'll have to pry my Effexor out of my cold dead hands! It helps so much with my fibromyalgia pain as well as my anxiety."

   
10

Glttrgrl8 (taken for 10 years or more) June 26, 2013

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"Been on this medicine for Fybromyalgia for 4 days and it has made a lot of difference already. I am on the very low dose at the moment 37.5mg and am titrating up to 75mg after the first week. I feel sick in the morning before I eat (which I don't usually do until lunch time) but after a coffee this feeling subsides enough to manage. I have tried about 6 other medicines over the past 12 months and the side effects of them all were intolerable. However if I can take this medicine with the effect it has already had then I will be happy."

   
7.0

The Bee (taken for less than 1 month) May 14, 2013

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"Was given this for depression and had no idea it would transform my life. After taking for just 1 day I noticed my pain was almost gone after suffering for years. I can't believe that only the day before I started venlafaxine I had to use crutches to go shopping because the pain in my legs and back when walking was excruciating. I've noticed I feel so much more relaxed than I have in years, my mood has improved, I feel almost excited that I can now get my life back. I am 45, have Ehlers Danlos Syndrome and fibromyalgia and wish I had known about venlafaxine years ago."

   
10

tjr67 (taken for less than 1 month) January 15, 2013

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"I am satisfied with this medicine except I have been very constipated since being on it."

   
7.0

auntiephyl (taken for 6 months to 1 year) August 30, 2012

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Effexor (venlafaxine): "I've been on Effexor for approximately two years. I recently had the extremely unpleasant side effects from coming off the drug, as I could not get a refill on my prescription for 6 days. I ended up in the ER due to a panic attack (never had one in my life before). It did reveal, however, that the medicine was not really working for me, as my pain level was virtually the same whether I was on it or not. Please make sure you gradually go off this medicine under the care of a Dr."

   
6.0

Anonymous (taken for 2 to 5 years) August 22, 2012

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"Took this medicine for depression, I didn't have a clue that it would take away my pain. I would guess it has taken away 90% of the pain. This has been the first antidepressant that I have been able to tolerate in 30 years. I thought I tried everything in the book but when my doctor was going over a list of antidepressants I said I have never tried one that started with a "V" before. I hit the jackpot!"

   
10

Anonymous (taken for 2 to 5 years) June 16, 2012

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"I've only started this medication about 3 weeks ago, I take 75mg/day. I've noticed a big difference when I exercise now. Normally a walk around the track or using my elliptical would have me in a ton of pain for the rest of the day. Now I can exercise without the all day pain anymore."

   
9.0

Anonymous (taken for less than 1 month) May 19, 2012

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"I suffer from chronic pain from degenerative disc disease, fibromyalgia, arthritis and depression. Doctor put me on this for my fibromyalgia. I found it has done wonders for my depression (got off Prozac), PMDD and fibromyalgia pain. I'm only 42 yrs old and suffer everyday of my life. This has given me some of my life back. As an added benefit I lost some weight."

   
9.0

lynannm September 12, 2011

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Effexor XR (venlafaxine): "It worked on the fibromyalgia pain, but it caused my brain to malfunction. I couldn't think, I became forgetful, I got 'lost and confused' in my own house, my head felt as if it was full of cobwebs and I was walking in a fog all the time, I'd wake up as tired as I had been when I went to bed unless I drank a few beers or had a couple of glasses of wine. I am now in pain AND depressed. Trying to locate a natural [herb/spice] for fibromyalgia pain and subsequent depression."

   
4.0

Auntie Coosa June 27, 2011

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Effexor (venlafaxine): "This does not work for my real fibro pain."

   
1.0

mom-in-pain February 24, 2011

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"Venlafaxine extended release in combination with low dose tramadol in the mornings has been extremely effective in controlling my symptoms. I'm glad to have found something that works! I get so much more work done each day, it's like a transformation."

   
7.0

Kenni November 11, 2010

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