User Reviews for Parnate

Parnate (tranylcypromine) for Depression: Been on Parnate (tranylcypromine) for about 17 years. Like many others felt like a guinea pig when I was first diagnosed. Went through about a dozen different psychiatrists. They all just tried different meds trying to find one that would work. I or anyone else could have done that. One convinced me to have ECT which I did against my better judgement. It was a nightmare of torture! After the first two I lost all sense of time as well as my memory. I had 14 ECT treatments and was nothing more than a zombie! To get it to stop I said I wasn't depressed any more. Finally found a Dr. that used Parnate.

Parnate (tranylcypromine) for Depression: I have been on Parnate for 1 year now. I have been on many other antidepressants. Parnate has certainly worked for me. There are still some days that I feel just a little down but nothing compared to the major depression I had suffered. Before my doctor Put me on Parnate I had been hospitalized and underwent ECTS successfully. Now I feel good finally. I do have to watch the foods because I hyperventilate and also severe diarrhea. Plus I am on 50mg of Seroquel in the morning and 100mg in the evening. Parnate is 10 mg x a day, which is low compared to some people.

Parnate (tranylcypromine) for Depression: 5 years on Parnate. Have tried numerous antidepressants and Psycho Drugs, this is only one that has worked. Also take 2 mg/day Suboxone it helps some how.

Parnate (tranylcypromine) for Depression: It may include some side effects, I used and I prefer Parnate with some side effects vs depression that's my experience.

Parnate (tranylcypromine) for Depression: I have been treated for severe cyclic depressions (atypical), anxiety, and OCD since college and I am 47. Without effective medication, my illness is debilitating. In 1993, after trying many different antidepressants, I urged my psychiatrist to prescribe me the monoamine oxidase inhibitor, Nardil. WOW....somebody switched the lights on and the symptoms off. 90% of the time I was in remission with only brief minor periods of symptoms. Nardil was reformulated and stopped working, so I switched to Parnate. 160mg/day give 100% symptom relief (with 1200mg/day lithium). I mentally feel like I'm 20, bursting with mental energy. Many considered me brilliant prior to Parnate; but after years on it, my cognitive skills, retention, and creativity reached a new level.

Parnate (tranylcypromine) for Depression: Side effects are terrible. They inlcude diarrhea, dry mouth, in my case weight gain, it also made me agitated. I have been trying to withdraw from it and now have neuromuscular symptoms of cramping, teeth grinding, eye blinking.

Parnate (tranylcypromine) for Depression: I give it a 10 and I would give SSRI's and SNRI's only a 5. It's our first experience with MAOI's and its still early days. But what a difference with fatique (none). Other side effects in our case are minimal or non existent. I wonder what % of people actually notice severe side effects (maybe less then 20%?). It appears that MAOI's are well known these days. I presume it's because they are old generic drugs (not covered by active patents) and hence will not get high advertising budgets from the pharmaceutical companies. I also presume that many GP's have no knowledge of this class of drugs or these are too risky, adverse (side effects) to recommend a trial. It took us at least 7 years of battling depression and fatigue before we found out!

Parnate (tranylcypromine) for Depression: After 15 years of SSRIs and SNRI's, I was told to consider shock therapy or Parnate. Parnate is a miracle drug as far as I am concerned. At 47, I seem to have the energy that I had in my 20s and 30s. I am taking Ambien to deal with the side effect of insomnia and its working great. For once I seem to be able to synchronize up with the rest of the world. The special diet required has not been a problem so far. I seem to have a problem with almonds, but cheese pizza (non-aged cheese only!) is still okay.

Parnate (tranylcypromine) for Depression: I have had Parnate prescribed since 1987, when I was 35. After many years feeling like a an "anti-depressant guinea pig", I finally had clarity and with my psychiatrist's recommendation was able to manage my life while professionally succeeding. I don't miss the foods I can't eat, but value the relationships I've been able to maintain.

Parnate (tranylcypromine) for Depression: Even though there are many food restrictions, food I dearly love and miss, Parnate has given me my life back. I have been suffering from anxiety and depression all my life and this is the first drug that has actually helped. Thank you for giving me life again.