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Ultram ER User Reviews & Ratings

Ultram ER has an average rating of 8.0 out of 10 from a total of 20 reviews on Drugs.com. 81% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Ultram ER

  • Jkish
  • May 30, 2011

For Back Pain "Been on it for three day, and feel like myself again. Decompression, fusion, injection therapy, muscle relaxers, opiates, nerve blockers, NSAIDs. Nothing has given me long term relief the way Ultram ER has. Aside from the dependence issues, I think I found my wonder drug. I have degenerative disk disease and spinal stenosis."

10 / 10
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125 Report
  • Nana
  • Taken for 6 months to 1 year
  • January 11, 2020

For Chronic Pain "I have a several health issues including Fibromyalgia. My Specialist had tried everything on me and nothing gave me any relief. Once they put me on this medication I was actually able to get up and move. I had to change one of my Doctors and she didn’t want me on this high of a dosage. Since lowering the mg. And it not being extended release I am back to having chronic pain."

10 / 10
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51 Report
  • happy...
  • October 22, 2007

For Pain "I took generic Tramadol 50 mgs for years and it did not help me. When I heard about Ultram ER 200 mgs I asked my doctor if I could try it and she said "Yes." I started taking it and the difference in my pain level was amazing. I ran out of it and in the interim my pain level escalated beyond belief. I will never be without this RX ever again. It keeps my pain at a level that is tolerable. It made a tremendous difference in the quality of my life!"

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108 Report

Frequently asked questions

  • heloguy
  • March 5, 2008

For Pain "I am a Helicopter pilot for the US Army and I have Chronic upper back pain. I am on the 200mg Ultram and it is a life savor. It still allows me to fly and controls the pain. My only issues with this drug is it tends to make me itch and I can't take it before bed or i will be awake all night. I have been taking it as needed for the past 6 months."

9 / 10
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85 Report
  • OGirl
  • February 11, 2015

For Chronic Pain "Could not stay on Norco long term. Tried the IR, Tramadol but it did nothing. The Tramadol ER was very very different and works wonderfully. I rarely experience head pain over a 3-4 pain scale. I take this daily, every morning 100mg."

8 / 10
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46 Report

Are you taking this medicine?

  • Nurse...
  • May 7, 2009

For Pain "I have adhesions related to multiple abdominal surgeries and some nerve damage as well. I was on Vicodin for 6 months and was referred to a pain clinic. Being a nurse I had seen Ultram used in the hospital with good pain control. I suggested I try it and stop the Vicodin. It was an incredibly easy transition and the benefits were immediate. I too have noticed a definite mood stabilizing. I was having mood swings on the Vicodin that were affecting my relationships with others. I feel calmer and my pain is nearly gone at 200mg daily. I am so thankful for having relief. I think it's a wonderful drug."

10 / 10
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54 Report
  • Taffyt
  • Taken for 6 months to 1 year
  • November 12, 2017

For Chronic Pain "Tramadol extended-release 100mg reduces my herniation disc (neck) and pinched nerve pain from an 8 pain level to a 2. Sometimes need an extra 50mg of IR and alternate advil and Tylenol for added pain relief."

9 / 10
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27 Report

More FAQ

  • Anonymous
  • April 9, 2010

For Pain "I had an accident at work about 4 years ago which injured my neck and back. After taking generic tramadol for a couple of years and constantly having to up my dosage I saw a new doctor who switched me to 300 mg Ultram ER, what a difference! I have been taking it for 2 years now and I can't imagine what I would do without it."

10 / 10
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45 Report
  • Tiny...
  • Taken for less than 1 month
  • September 7, 2017

For Chronic Pain "I broke my knee, and all the cartilage came out of the back, I hate NARCOTICS, having bipolar issues, as well, . Ultram is right in the middle, takes pain away , ENOUGH, so I don't have to concentrate on me!"

8 / 10
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24 Report
  • Funct...
  • January 19, 2010

For Pain "I was in a car accident in April 2009. My doctor put me on Flexeril, hydrocodone, and ibuprofen. The hydrocodone helped me stay functional but he took me off of them. I was very careful with taking them but I guess he thought I didn't need them. So after that, I found out after talking to others that he should have sent me to an Orthopedic. Well, I got a new doctor who referred me to an awesome Orthopedic doctor. He checked me out and took me off the Flexeril and put me on Tramadol ER. He also referred me to a wonderful physical therapy wellness center. Tramadol has given me my life back!"

10 / 10
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42 Report
  • dan...
  • January 6, 2009

For Pain "I am now 19 years old. 2 years out of HIgh School I severely broke my hand from a fight. I have never felt so much pain in my life. I underwent 3 surgeries, 3 plates and 24 screws later my hand was somewhat normal still a lot of pain. Now im getting ready to leave for the United States AirForce and can not take narcotic pain medication. My doctor recommended 200mg Ultram ER. IT WORKS WONDERS and it doesn't show in my drug screening. I never thought I could take one pill a day and be pain free."

8 / 10
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43 Report
  • trowe
  • March 22, 2009

For Fibromyalgia "I have had Fibromyalia for years and have been prescribed many different pain medicines. I have also been seeking less pharmaceutical ways of dealing with my pain. One doctor prescribed tryptophan to me and I thought it was great and have had to use less pain medicines because of it, however I did not know that it was classified as an SSRI so when my new doctor prescribed tramadol to me and bumped me right up to the highest dose and I took it with my tryptophan I got really really sick. It took me a few days to figure out what was going on but I was having a major drug interaction called serotonin syndrome. Be careful. Yes, this drug works wonders on pain but can be dangerous with many other drugs."

2 / 10
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38 Report
  • Scoli...
  • April 1, 2011

For Back Pain "I had scoliosis surgery about 30 yrs ago. Was in an auto accident herniated cervical and lumbar discs. Now fused T1-S1. Lumbar fusion resulted in nerve damage with pain radiating through right leg to my toes. Lyrica and Neurontin didn't help. Tramadol worked wonders. I take 2-50mg tabs and they get me moving. But they keep me up at night the pain keeps me up all night too so I take temazepam for sleep. Now I'm trying the extended release version at night hoping the lag time until they start working will allow me some sleep and I'll feel better when I wake up."

8 / 10
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34 Report
  • Kooli...
  • January 24, 2010

For Pain "I have peripheral neuropathy that was originally misdiagnosed as fibromyalgia, until I demanded real tests. I've tried Duragesic, Oxycontin, Vicodin, Tylenol with Codeine (developed an allergy to), Lyrica, as well as various other NSAIDS and muscle relaxers. I hated taking narcotics, there is a big family history of drug abuse and it really made me worried that maybe I would start acting like them. I would say that Ultram ER 300mg plus 2 of the 50mg tabs per day as needed really works well. I do also take 1500mg of gabapentin a day, alprazolam to sleep if needed, and Soma occasionally (maybe 2-3 x/ month). I also use Lidoderm patches and TEDS. I now can go to college again and don't feel doped up."

8 / 10
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30 Report
  • Chiqu...
  • March 3, 2008

For Pain "I had been taking Ultram 50mg for two years and my Doctor decided to take me off of it because i was taking 4 tablets per day. Since then my doctor has put me on other meds which have not helped. I recently read about Ultram ER and I have a doctors appt tommorrow. I am going to mention this to my doctor to try because i think a one a day pill is exactly what I need. I will let you all know how it goes. I pray this works because i am tired of taking pill after pill."

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31 Report
  • lwrbk...
  • November 21, 2010

For Pain "I had surgery for scoliosis with spinal fusion 27 years ago. Since then, my neck and lower back (without fusion) have been collapsing, curving, and I have been diagnosed with degenerative disc disease. The pain began to extend to my hips and shoulders and it became impossible to function. I had difficulty getting up and moving around, and more and more difficulty doing basic daily chores. (I am a 51 y/o woman with 5 children - no wonder, right? ha ha). Anyway, my doctor prescribed Ultram ER 100mg for me about 5 years ago and it has given me relief for the most part - until the last year. I think I need to increase the dosage as I know my back is worse and the pain is getting worse, however, Ultram has been a life saver."

8 / 10
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26 Report
  • Anonymous
  • November 28, 2009

For Pain "I was diagnosed with Multiple Sclerosis 2 years ago. At the same time I was in early recovery for addiction to pain killers (prescribed for pain,if your pain never stops you continue to use as prescribed and you are addicted). I had to have something so my Doctor told me about tramadol. I take 4-6 50 mg a day for pain. No side effects. Don't know how I would have got along without it."

8 / 10
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27 Report
  • chronic...
  • August 4, 2008

For Pain "I have chronic lower lumbar pain from a bone disorder that affects mostly my lower back. Pain can be excruciating at times. I was taking the tramadol 50 mg tablets for a few years they helped some but I had to take more and more of them. My doctor put me on the tramadol ER tablets so I take 1 tablet a day. It is great. With one 300 mg tablet a day I can function fine. It gives great pain relief."

9 / 10
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  • KMU
  • March 24, 2008

For Pain "I have suffered from TMJ issues for many years and was prescribed many pain meds but the narcotics made me very ill. I started taking Ultram ER 200mg and for once I could actually function in the real world! I recommend anyone needing long-term pain relief to look into Ultram ER"

9 / 10
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27 Report
  • autmn...
  • May 3, 2010

For Pain "My doctor prescribed ULTRAM ER 200 for lower back pain and sciatica. I was taking 1 tablet twice a day. For 2 or 3 days it seemed to work great. Then I started having side effects. I had mild dizziness and a slight upset stomach. I took Ultram ER for a total of 9 days. The dizziness became severe, I was lethargic but not able to sleep for more than 2 or 3 hours a night, and the nausea had increased. I stopped taking ultram ER and it took 12 days for the side effects to subside. The doctor said I had an allergic reaction to this medication."

1 / 10
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23 Report
  • DeniseP
  • December 6, 2008

For Pain "I had spinal fusion in lower lumbar region 9 years ago. I was fine until August '08. I had such severe sciatic pain doctor progressively put me on Ultram ER 200mg 1x / day. It worked great. Pain went away after 4 months. I stopped taking Ultram and now I am dealing with withdrawal symptoms. PAY ATTENTION to warnings about long term usage."

8 / 10
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24 Report
  • Anonymous
  • July 11, 2008

For Pain "I found tramodol to be very effective in controlling my back pain. I was able to use the minimum dose for the most part, but knew that I could take another half pill if the pain was more severe, usually in the morning. As the pain decreased, I did not feel the need to take the medicine as often, and was able to get off of it easily. I could function well while on this drug at the minimum dose."

9 / 10
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25 Report
  • Harry...
  • September 11, 2009

For Pain "This is an exceptional drug for pain relief but the side effects far outweigh the pain relieving benefits. I took Ultram ER,300 MG for 3 months for low back pain and like I said it was a savior for my pain. However, I started to have some strange dreams with muscle spasms, constipation and extreme fatigue. I stopped the drug about 10 days ago and have finally started to feel better. I am 73 years old and in good health, except for the back pain."

3 / 10
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22 Report
  • monak...
  • November 19, 2011

For Back Pain "2005 started taking tramadol 50mg, and the within a few months started on 100mg time release. These past few months I feel the medication hasn't helped like in the beginning. Sciatica pain 24/7, Thursday had another round of epidural, and doctor wants me off tramadol. Well tonight I've had such bad anxiety I can't sleep. I thought he would ween me off this medicine, like all other medicine in this category! Will call the doctors office Monday, this is ridiculous to be miserable at night, due to the doctors advise. I'm tempted to just take a pill just to get some sleep, I have a little tingly on the right leg, but not in any pain. Hope this epidural works this time. Back in 2006 it did not help. "

7 / 10
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15 Report
  • nic
  • Taken for 1 to 2 years
  • March 11, 2019

For Chronic Pain "Ultram ER pumps pain relief through my body for the entire day and night. I gave up hydrocodone for this drug and I am very pleased"

10 / 10
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36 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.